orari e date aggiornati quando saranno noti gli anticipi/posticipi
| GG | data | ora | incontro | risultato |
|---|---|---|---|---|
| Andata | ||||
| 1^ | 29-08-2010 | 20:45 | Milan – Lecce | 4 – 0 |
| 2^ | 11-09-2010 (sab) | 20:45 | Cesena – Milan | 2 – 0 |
| 3^ | 18-09-2010 (sab) | 20:45 | Milan – Catania | 1 – 1 |
| 4^ | 22-09-2010 (mer) | 20:45 | Lazio – Milan | 1 – 1 |
| 5^ | 25-09-2010 (sab) | 18:00 | Milan – Genoa | 1 – 0 |
| 6^ | 02-10-2010 (sab) | 20:45 | Parma – Milan | 0 – 1 |
| 7^ | 16-10-2010 (sab) | 18:00 | Milan – Chievo | 3 – 1 |
| 8^ | 25-10-2010 (lun) | 20:45 | Napoli – Milan | 1 – 2 |
| 9^ | 30-10-2010 (sab) | 20:45 | Milan – Juventus | 1 – 2 |
| 10^ | 07-11-2010 | 15:00 | Bari – Milan | 2 – 3 |
| 11^ | 10-11-2010 (mer) | 20:45 | Milan – Palermo | 3 – 1 |
| 12^ | 14-11-2010 | 20:45 | Inter – Milan | 0 – 1 |
| 13^ | 20-11-2010 (sab) | 20:45 | Milan – Fiorentina | 1 – 0 |
| 14^ | 27-11-2010 (sab) | 18:00 | Sampdoria – Milan | 1 – 1 |
| 15^ | 04-12-2010 (sab) | 20:45 | Milan – Brescia | 3 – 0 |
| 16^ | 12-12-2010 | 12:30 | Bologna – Milan | 0 – 3 |
| 17^ | 18-12-2010 (sab) | 20:45 | Milan – Roma | 0 – 1 |
| 18^ | 06-01-2011 (gio) | 15:00 | Cagliari – Milan | 0 – 1 |
| 19^ | 09-01-2011 | 15:00 | Milan – Udinese | 4 – 4 |
| Ritorno | ||||
| 20^ | 16-01-2011 | 20:45 | Lecce – Milan | 1 – 1 |
| 21^ | 23-01-2011 | 20:45 | Milan – Cesena | 2 – 0 |
| 22^ | 29-01-2011 (sab) | 20:45 | Catania – Milan | 0 – 2 |
| 23^ | 01-02-2011 (mar) | 20:45 | Milan – Lazio | 0 – 0 |
| 24^ | 06-02-2011 | 15:00 | Genoa – Milan | 1 – 1 |
| 25^ | 12-02-2011 (sab) | 18:00 | Milan – Parma | 4 – 0 |
| 26^ | 20-02-2011 | 15:00 | Chievo – Milan | 1 – 2 |
| 27^ | 28-02-2011 (lun) | 20:45 | Milan – Napoli | 3 – 0 |
| 28^ | 05-03-2011 (sab) | 20:45 | Juventus – Milan | 0 – 1 |
| 29^ | 13-03-2011 | 12:30 | Milan – Bari | 1 – 1 |
| 30^ | 19-03-2011 (sab) | 20:45 | Palermo – Milan | 1 – 0 |
| 31^ | 02-04-2011 (sab) | 20:45 | Milan – Inter | 3 – 0 |
| 32^ | 10-04-2011 | 20:45 | Fiorentina – Milan | 1 – 2 |
| 33^ | 16-04-2011 (sab) | 20:45 | Milan – Sampdoria | 3 – 0 |
| 34^ | 23-04-2011 (sab) | 19:00 | Brescia – Milan | 0 – 1 |
| 35^ | 01-05-2011 | 15:00 | Milan – Bologna | 1 – 0 |
| 36^ | 07-05-2011 (sab) | 20:45 | Roma – Milan | 0 – 0 |
| 37^ | 14-05-2011 (sab) | 20:45 | Milan – Cagliari | 4 – 1 |
| 38^ | 22-05-2011 | 20:45 | Udinese – Milan | 0 – 0 |
Soste qualificazioni a Euro 2012 05.09 – 10.10.2010 – 27.03.2011
Pausa nel periodo Natale – Capodanno dal 26.12.2010 al 03.01.2011
